News & Medical Papers


For current guidelines and updates from within the arrhythmia healthcare community please visit Arrhythmia Watch.

Postural modification to the standard Valsalva manoeuvre for emergency treatment of supraventricular tachycardias (REVERT): a randomised controlled trial

27 August 2015
The Lancet

Background The Valsalva manoeuvre is an internationally recommended treatment for supraventricular tachycardia, but cardioversion is rare in practice (5–20%), necessitating the use of other treatments including adenosine, which patients often find unpleasant. We assessed whether a postural modification to the Valsalva manoeuvre could improve its effectiveness.

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Bristol-Myers Squibb and Pfizer to Present New Data on Eliquis (apixaban) at the ESC Congress 2015

26 August 2015
Business Wire

"The Bristol-Myers Squibb and Pfizer Alliance is pleased to share 22 abstracts, which include important Eliquis data from both clinical trials and real-world analyses, at one of the world’s largest and most influential cardiovascular meetings," said Douglas Manion, M.D., head of specialty development, Bristol-Myers Squibb.

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HARMONY: Ranolazine, dronedarone combination benefits patients with paroxysmal AF

Healio Cardiology Today, 26 August 2015

Published data from the HARMONY trial confirm a previous report that moderate-dose ranolazine plus reduced-dose dronedarone was well-tolerated and reduced atrial fibrillation burden, according to a report in Circulation: Arrhythmia & Electrophysiology.

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Lay Summary for research publication on emergency treatment for SVT (supraventricular tachycardias)

25 August 2015

This lay summary is to inform study volunteers, patients and their carers of the outcome of this research and how the results may help them to better manage their condition.

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Taxonomy of the burden of treatment: a multi-country web-based qualitative study of patients with chronic conditions
BMC Medicine, 30 July 2015

Management strategies for patients with chronic conditions are becoming increasingly complex,
which may result in a burden of treatment for patients.

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A-Fib Drug Passes New Test

HCP Live, 27 July 2015

A new sub-analysis of data from the trial known as ROCKET-AF shows that rivaroxaban (Xarelto/Janssen) works as well in patients who have both non-valvular atrial fibrillation (AF) and diabetes as in similar AF patients without diabetes.

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Accolade Pacing Systems

bostonscientificmail.eu, 12 May 2015
Discover the World’s First 3T MR-Conditional Pacemaker
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Cardiac Rhythm News

www.cxvascular.com, 7 May 2015
Follow the link below to view 'Top stories', 'Features' and 'Industry News' from BIBA Medical Ltd
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QiC Awards 2015

Quality in Care (QiC) Anticoagulation is an awards programme to recognise, reward and share good practice in anticoagulation management, education and patient care. The QiC Anticoagulation programme is comprised of a recognition event and subsequent dissemination opportunities for finalists to share good practice and demonstrate the benefits and adaptability of their initiatives to a wider healthcare audience. Gaining recognition through QiC Anticoagulation means an initiative has been highlighted by the NHS, patients and industry as improving patient outcomes and standards of care in the treatment and prevention of blood clots.
Visit website

Practices to provide warfarin clinics under CCG agreement

pulsetoday.co.uk, 9 April 2015
A CCG-GP ‘partnership’ agreement in Barnsley will fund GPs for visiting elderly or housebound patients at home to conduct medicines reviews and discuss end-of-life care, and increase the number of procedures that can be delivered by practices.
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Meta-analysis: Oral anticoagulants superior to warfarin, closure device for stroke prevention

healio.com, 7 April 2015
A systematic review and meta-analysis of randomized controlled trials indicated treatment with novel oral anticoagulants was superior to warfarin and a left atrial appendage closure device for the prevention of stroke in patients with nonvalvular atrial fibrillation.
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National Audit of Cardiac Ablation 2013-14

27 March 2015

The National Cardiac Rhythm Management Ablation Audit is managed by the National Institute for Cardiovascular Outcomes Research (NICOR), which is part of the National Centre for Cardiovascular Prevention and Outcomes, based at University College London. Specialist clinical knowledge and leadership is provided by the British Cardiovascular Society and British Heart Rhythm Society. The strategic direction and development of the audit is determined by the Audit Steering Group. This includes major stakeholders in the audit, including cardiologists, the professional societies, physiologists, commissioners and patient group representatives.

Download report

Read response from AF Association

ESC webinar on cardiac resynchronisation therapy: what do the ESC guidelines tell us?

ESC Education, April 2015
On 23 April 2015 from 18:00 to 19:00 CET, join Carsten Israel and Haran Burri for a live webinar focusing on the implementation of the latest ESC Guidelines on "Cardiac Pacing and Cardiac resynchronisation Therapy" through relevant clinical cases.

Support call for a National Service Delivery Model for warfarin patients

scottish.parliament.uk, March 2015
Petition to the Scottish Parliament launched to ensure that ensure that all NHS boards have the resources to assess warfarin patients who request (i.e. self-present) for self-testing and/or self-management their condition.

Currently no such model exists for Scotland's 80,000 warfarin patients.

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Oral anticoagulants for stroke prevention in atrial fibrillation | Ten points to remember

acc.org, 27 March 2015
The following are 10 points to remember about anticoagulants for stroke prevention in atrial fibrillation (AF).
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Home exercise safe, improves CV performance in adults with ICDs

healio.com, 26 March 2015
In a new study, prescribed home exercise was safe and improved CV performance without increasing the occurrence of shocks, hospitalizations or death among adults with an implantable cardioverter defibrillator for primary or secondary prevention.
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Diploma in Syncope and Related Disorders at the Royal College of Physicians of Ireland

Syncope Trust And Reflex anoxic Seizures (STARS), January 2015
This course is the initiative of STARS Trustee, Professor Rose Ann Kenny and Dr Conal Cunningham. Already the positive feedback and uptake is more than encouraging. Syncope units must be the way forward for the future and for anyone whose hospital is considering this then early registration of interest for 2015 is recommended.

Learn more

2013-14 Cardiac Rhythm Management National Report published

ucl.ac.uk, February 2015
The latest annual report, Heart Rhythm Device Implants and Cardiac Ablation, is now available.
Read online

ICD therapy effective in patients with Brugada syndrome

healio.com, 25 March 2015
In patients with Brugada syndrome, implantable cardioverter defibrillator was effective and treated potentially lethal arrhythmias in 17% of patients during a 20-year, single-center study.
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Amiodarone associated with acute pancreatitis in patients with AF

healio.com, 24 March 2015
Acute pancreatitis could be an adverse effect of amiodarone use in patients with atrial fibrillation, according to results of a nested case-control study.
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Boston Scientific Announces First U.S. Commercial Procedures With The WATCHMAN™ Left Atrial Appendage Closure Device

prnewswire.com, 24 March 2015
This week, three patients in the United States received the first implants of the Boston Scientific Corporation (NYSE: BSX) WATCHMAN™ Left Atrial Appendage Closure (LAAC) Device.
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Now published: NICE adoption resources to support NICE guidance that aims to enable people on long-term anticoagulation therapy to self-monitor their blood clotting

National Institute for Health and Care Excellence (NICE), March 2015
These adoption resources have been designed for both clinical and non-clinical staff who are planning to adopt the devices recommended in this guidance (NICE diagnostics guidance DG14 on self-monitoring coagulometers, released September 2014).
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Major Implications for new AF Guidelines

hcplive.com, 23 March 2015
A new analysis finds that updates to atrial fibrillation (AF) treatment guidelines will encourage American doctors to prescribe oral anticoagulants to almost 1 million more patients.
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Ablation bests amiodarone for treating AF in patients with Heart Failure

medscape.com, 20 March 2015
Long-term results from the Ablation vs Amiodarone for Treatment of Atrial Fibrillation in Patients with Congestive Heart Failure and an Implanted ICD/CRT-D (AATAC-AF) suggest that the procedure is significantly superior to the medication in relieving persistent AF.
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AF Ablation at Mitral-Valve Surgery Works, but Without Clinical Gains in Randomized Trial

medscape.com, 20 March 2015
SAN DIEGO, CA — A randomized trial of patients with atrial fibrillation undergoing mitral-valve surgery largely confirmed the 1-year safety and efficacy ...
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Ted Robbins: 'I’m lucky to be here' says Phoenix Night comic as he thanks medics that saved his life

manchestereveningnews.co.uk, 22 March 2015
After his dramatic opening night collapse during the Phoenix Nights stage show, Ted Robbins talks to Amanda Killelea about his recovery and how grateful he is.
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AF ablation with nMARQ system

prurgent.com, 23 March 2015
Arizona Heart Rhythm Center now with Largest US experience using nMARQ™ Multi-electrode Pulmonary Vein Isolation System for treatment of Paroxysmal Atrial Fibrillation.
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Women up to three times more likely to die after stroke

independent.ie, 23 March 2015
Women are dying from stroke three times more often than men in some parts of the country.
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Video: Real-world versus clinical trial data with NOACs

radcliffecardiology.com, 20 March 2015
Presented by Paulus Kirchhof, Chair in Cardiovascular Medicine Cardiovascular and Respiratory Sciences at University of Birmingham, UK
Watch video

Weight loss reduces atrial fibrillation

hcplive.com, 19 March 2015
Rajeev Pathank and colleagues at the Centre for Heart Rhythm Disorders at the University of Adelaide, Canberra, Australia studied AF in 355 patients with a body mass index of 27.
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Ablation associated with lower long-term risk of stroke compared to cardioversion in patients with AF

hcplive.com, 18 March 2015
An analysis of more than 20,000 records indicates that patients who choose catheter ablation rather than cardioversion for atrial fibrillation (AF) face an elevated stroke risk immediately after the procedure but a lower stroke risk thereafter.
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Community Resuscitation Strategy - Northern Ireland

Building on a commitment in the Service Framework for Cardiovascular Health and Wellbeing, and working with a range of departments and agencies, DHSSPS has developed a Community Resuscitation Strategy for Northern Ireland. The aim is to increase survival for those who suffer an out-of-hospital cardiac arrest by having more people in the community trained to perform CPR and to use an automated external defibrillator.
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Heart failure patients need more counseling on defibrillators

hcplive.com, 15 March 2015
Heart failure patients have many treatment options, including--for some--getting an implantable defibrillator. But only about 1 in 5 hospitalized heart failure patients who might benefit from an implantable defibrillators gets pre-discharge counseling on that option, a Duke University study found.
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Increased bleeding risks in patients sensitive to warfarin: ENGAGE AF-TIMI 48 analysis

medscape.com, 14 March 2015
Boston Scientific Corporation announced that the FDA has approved the Watchman left atrial appendage closure device.
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FDA approves left atrial appendage closure device

healio.com, 14 March 2015
Boston Scientific Corporation announced that the FDA has approved the Watchman left atrial appendage closure device.
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First in-man study of miniaturised implantable cardiac monitor shows positive results

cxvascular.com, 12 March 2015
First in-man multicentre study of the miniaturised implantable cardiac monitor Reveal Linq (Medtronic) suggests the device is safe and provides adequate sensing capabilities to detect arrhythmias.
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Updated US guidelines suggest an increase by 19% in AF patients recommended for oral anticoagulation

cxvascular.com, 5 March 2015
An assessment of the 2014 American Heart Association (AHA), American College of Cardiology (ACC) and Heart Rhythm Society (HRS) guidelines concerning oral anticoagulation in atrial fibrillation indicates that two-thirds of patients who were not previously recommended for oral anticoagulation therapy are now recommended.
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'Digitizing' crosstalk among heart cells may help locate epicenters of heart rhythms

medicalxpress.com, 10 March 2015
A team of scientists led by Johns Hopkins cardiologist and biomedical engineer Hiroshi Ashikaga, M.D., Ph.D., has developed a mathematical model to measure and digitally map the beat-sustaining electrical flow between heart cells.
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Intracardiac thrombi rates lower with dabigatran, rivaroxaban, compared with phenprocoumon

healio.com, 6 March 2015
The prevalence of intracardiac thrombi was lower in high-risk patients with atrial fibrillation and flutter treated with direct oral anticoagulants compared with phenprocoumon, according to German researchers.
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Safer drug combination found for patients with high-risk atrial fibrillation

medicalxpress.com, 6 March 2015
Patients with high-risk atrial fibrillation, or AFib, often require one drug to regulate heart rhythm and a second drug to thin their blood and reduce the risk of stroke.
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CPR devices approved for paramedics

medpagetoday.com, 9 March 2015
The FDA approved the ResQCPR System of two devices for use by first responders doing cardiopulmonary resuscitation (CPR) on people in cardiac arrest.
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Atrial fibrillation patients on digoxin face increased risk of death

medicalxpress.com, 4 March 2015
Patients taking digoxin to control atrial fibrillation face a 27 percent greater risk of dying than atrial fibrillation patients who are not taking digoxin, according to an analysis of 19 studies involving more than 500,000 patients scheduled for presentation at the American College of Cardiology's 64th Annual Scientific Session in San Diego.
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Anemia linked to adverse outcomes in atrial fibrillation

medicalxpress.com, 4 March 2015
For patients with atrial fibrillation receiving anticoagulant treatment, the presence of anemia is associated with increased risk of thromboembolic events, bleeding complications, and mortality, according to research published online Feb. 13 in the Journal of Thrombosis and Haemostasis.
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Case Challenge: A Sudden Increase in INR

medscape.com, 4 March 2015
A 76-year-old man is admitted with increasing shortness of breath. He has a long history of chronic obstructive pulmonary disease (COPD) and has had a recent productive cough. He is admitted to the hospital and treated with amoxicillin, prednisone, codeine, and albuterol.
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ECGs for the faint hearted - interpreting ECGs

bjcardio.co.uk, March 2015
In this regular series ‘ECGs for the fainthearted’ Dr Heather Wetherell will be interpreting ECGs in a non-threatening and simple way. In this issue, we apply the knowledge gained so far to a situation that may be encountered in general practice.
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Manufacturer of dabigatran files for reversal agent in Europe

pmlive.com, 4 March 2015
Boehringer Ingelheim has surpassed its rivals in the novel oral anticoagulant (NOAC) category by filing a reversal agent for its Pradaxa drug in Europe.
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Portola announces full results from positive phase 3 ANNEXA(TM)-R study demonstrating that andexanet alfa rapidly and significantly reversed anticoagulant effect of factor Xa Inhibitor XARELTO

GlobeNewswire.com, 2 March 2015
Portola Pharmaceuticals (Nasdaq:PTLA) today announced full results from the first part of the Phase 3 ANNEXA™-R (Andexanet Alfa a Novel Antidote to the Anticoagulant Effects of fXa Inhibitors – Rivaroxaban) study, which is evaluating the safety and efficacy of andexanet alfa with the Factor Xa inhibitor XARELTO® (rivaroxaban) in healthy volunteers.
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Many with AF qualify for oral anticoagulation therapy under new guidelines

healio.com, 2 March 2015
Most patients with atrial fibrillation not recommended for oral anticoagulation under previous guidelines are now eligible for therapy based on the newest guidelines, according to a report published in JAMA Internal Medicine.
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Boehringer Ingelheim files BLA for antidote to dabigatran

healio.com, 2 March 2015
Boehringer Ingelheim announced that it has submitted a biologics license application to the FDA requesting an accelerated approval pathway for idarucizumab, an antidote to dabigatran.
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Subcutaneous-ICD patients may be able to undergo MRI scans at 1.5T safely

cxvascular.com, 26 February 2015
Subcutaneous implantable cardioverter-defibrillator patients may be safe to be exposed to magnetic resonance imaging (MRI) procedures at 1.5T with a pre-specified scanning and monitoring protocol.
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New guidance on managing anticoagulant-associated ICH

medscape.com, 27 February 2015
In the acute phase of oral anticoagulation-associated intracerebral hemorrhage (OAC-ICH), two factors can protect against hematoma enlargement: getting the international normalized ratio (INR) below 1.3 and getting the systolic blood pressure (BP) below 160 mm Hg within 4 hours, a new study shows.
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FDA grants orphan drug status to Factor Xa inhibitor antidote

healio.com, 26 February 2015
The FDA has granted orphan drug designation to andexanet alfa for the treatment of patients with serious, uncontrolled bleeding events or who require emergency surgery, according to a press release from the drug’s manufacturer.
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Non-medical ILR implants cost-saving

arwatch.co.uk, 25 February 2015
A service has been developed which can safely insert implantable loop recorders (ILRs) in a non-medical, non-catheter laboratory (cath lab) environment, according to a study published recently in the British Journal of Cardiology.
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AF type is better stroke predictor

arwatch.co.uk, 25 February 2015
Pattern of atrial fibrillation (AF) is a strong independent predictor of stroke risk in non-anticoagulated patients, and may help to assess the risk/benefit for anticoagulant therapy, especially in lower risk patients, according to a study published recently in the European Heart Journal.
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Periprocedural anticoagulants safe for patients undergoing cardioversion or ablation for AF

healio.com, 24 February 2015
Warfarin, dabigatran and rivaroxaban are safe periprocedural anticoagulation options for patients undergoing cardioversion or ablation for atrial fibrillation, according to researchers in Canada.
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Scientists identify key protein behind heart's 'metronome'

medicalnewstoday.com, 23 February 2015
An important feature of a healthy heart is its ability to maintain a steady beat. Even a slight faltering in the heart's rhythm can cause sudden death. Now, a new study identifies a key protein that helps maintain the heart's "metronome."
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Cutting-edge heart model predicts changes in the heart that can lead to AF

hcplive.com, 19 February 2015
A paper from a pair of physicists may reveal significant new information about the causes of atrial fibrillation (AF) and help to make cardiac ablations a more effective treatment for the condition.
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Cardiac or other implantable electronic devices and sleep-disordered breathing - implications for diagnosis and therapy

radcliffecardiology.com, February 2015
Sleep-disordered breathing (SDB) is of growing interest in cardiology because SDB is a highly prevalent comorbidity in patients with a variety of cardiovascular diseases.
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Remote monitoring for follow-up of patients with implantable cardiac electronic devices

radcliffecardiology.com, February 2015
Lead and device performance monitoring is a physician responsibility and represents a challenge due to the number and complexity of implanted systems and the increased number of advisories during the last 10 years.
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Patients with AF, intermediate stroke risk should receive anticoagulation, says group

medscape.com, 18 February 2015
TAIPEI, TAIWAN — For men with atrial fibrillation (AF) who tick at least one box on the CHA2DS2-VASc risk-factor score sheet, the risk of ischemic stroke ranges from 1.96% per year to as high as 3.50%, depending on the specific risk factor composing the score, according to the results of a new analysis.
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Oral anticoagulation recommended for patients with AF, one additional stroke risk factor

healio.com, 16 February 2015
In a real-world cohort of patients in Taiwan, patients with atrial fibrillation and at least one additional risk factor for stroke were at high risk for ischemic stroke and researchers recommended that oral anticoagulation be considered in this patient population.
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Limit Hydroxyzine use to reduce cardiac risks, EU regulators say

medscape.com, 13 February 2015
Physicians should take certain precautions in prescribing the first-generation antihistamine hydroxyzine to minimize the drug’s risk for potentially fatal heart arrhythmias, the European Medicines Agency (EMA) announced today.
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Assessing bleeding and AF-stroke risk to achieve best patient outcome

medscape.com, 13 February 2015
At the 2014 ESC meeting, his group (lead author Dr TF Chao [Taipei Veterans General Hospital, Taiwan]) presented a Taiwanese registry study[7] showing that untreated CHA2DS2-VASc (CHA2DS2-VASc-1 for males, CHA2DS2-VASc-2 for females) patients have annual event rates in the range of 2% to 3% per year.
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Insertable cardiac monitors effective, provide value for poststroke AF

healio.com, 12 February 2015
Two studies of insertable cardiac monitors presented at the International Stroke Conference demonstrated that the devices were effective for the identification of atrial fibrillation in patients previously diagnosed with cryptogenic stroke and cost effective for the prevention of recurrent stroke.
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ENSURE-AF: Largest trial ever to explore novel oral anticoagulation in AF patients undergoing cardioversion

cxvascular.com, 10 February 2015
Results of the X-VERT trial, presented at the European Society of Cardiology meeting (ESC; 30 August–3 September, Barcelona, Spain), showed that rivaroxaban (Bayer/Janssen Pharmaceuticals) appears to be an effective and safe alternative to vitamin K antagonist (VKA) therapy in patients with non-valvular atrial fibrillation who are undergoing elective cardioversion (electrical or pharmacological).
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Phase 3 ANNEXA-R study of andexanet alfa and factor Xa inhibitor Xarelto meets primary endpoint

cxvascular.com, 5 February 2015
Portola has announced topline results from the first part of the phase 3 ANNEXA-R (Andexanet alfa a novel antidote to the anticoagulant effects of factor Xa inhibitors – rivaroxaban) study, which is evaluating the safety and efficacy of andexanet alfa with the factor Xa inhibitor Xarelto (rivaroxaban).
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Real-world multicentre study shows positive outcomes with left atrial appendage occlusion for stroke prevention in AF

cxvascular.com, 11 February 2015
The largest study using the Amplatzer Cardiac Plug (St Jude Medical) for left atrial appendage occlusion has shown a high procedural success rate and favourable outcomes for prevention of atrial fibrillation-related thromboembolism.
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Implantable cardioverter-defibrillators May Provide Little Benefit When Implanted Over Age 70

hcplive.com, 12 February 2015
Implantable cardioverter-defibrillators (ICDs) may not benefit all patients to the same degree, as their effectiveness seems to diminish somewhat with the advancing age of the patient, according to a review published online Feb. 10 in Circulation: Cardiovascular Quality Outcomes.
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Effectiveness of implanted defibrillators may depend on patient's age

medicalxpress.com, 10 February 2015
Implantable cardioverter-defibrillators (ICDs) prolong survival among heart patients who face a high risk for sudden cardiac death, a new review of research indicates.
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Novel algorithm led to low rate of inappropriate ICD shocks

healio.com, 9 February 2015
A novel discrimination algorithm designed to distinguish between true ventricular arrhythmias and other rhythms was associated with a low rate of inappropriate shocks in patients with single- and dual/triple-chamber implantable cardioverter defibrillators, according to new data from the PainFree SST study.
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Basildon Hospital now running one of the biggest INR self-testing programmes in England

echo-news.co.uk, 6 February 2015
BASILDON Hospital is one of the leading centres for a programme which gives pocketsized monitors to patients at risk of blood clots to test their blood at home.
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An arrhythmia specialist nurse improves patient care in arrhythmias treated with dronedarone

bjcardio.co.uk, February 2015
The European Medicines Agency (EMA) has mandated that patients treated with dronedarone have regular monitoring. An arrhythmia specialist nurse (ASN) took over the care of patients on dronedarone in 2012.
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Experiences from a non-medical, non-catheter laboratory implantable loop recorder (ILR) service

bjcardio.co.uk, February 2015
This paper describes the experiences of developing a non-medical, non-catheter laboratory (cath lab) based implantable loop recorder (ILR) service.
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Comparing the four NOACs

medpagetoday.com, 2 February 2015
With four new oral anticoagulants (NOACs) to chose from, even the most experienced clinicians face a quandary: which NOAC is the best choice for the patient?
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Head CT scans may be overused in Emergency Departments

medscape.com, 2 February 2015
Most patients presenting to the emergency department (ED) with syncope or dizziness may not benefit from a computed tomography (CT) scan of the head unless they are older than 60 years, have a focal neurologic deficit, or have a history of recent head trauma, researchers have found.
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CardioComm solutions to initiate sales of the Heartcheck(TM) ECG Pen device in pharmacies across Canada

marketwatch.com, 2 February 2015
The HeartCheck(TM) PEN will be made available in approximately 602 Shoppers Drug Mart Pharmacies by February 2015 which will coincide with the start of Heart Month.
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FDA approves ablation catheter with flexible tip to treat cardiac arrhythmias

healio.com, 28 January 2015
St. Jude Medical announced that the FDA has approved an ablation catheter with a flexible tip for treatment of patients with cardiac arrhythmias.
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Chinese University of Hong Kong advocates atrial fibrillation screening and drug education to reduce risk of stroke among elderly

healthcanal.com, 28 January 2015
The prevalence of Atrial Fibrillation (AF) grows with the ageing population. According to global research, one in every five people aged 65 years and above will develop AF.
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Diploma in Syncope and Related Disorders at the Royal College of Physicians of Ireland

Syncope Trust And Reflex anoxic Seizures (STARS), January 2015
This course is the initiative of STARS Trustee, Professor Rose Ann Kenny and Dr Conal Cunningham. Already the positive feedback and uptake is more than encouraging. Syncope units must be the way forward for the future and for anyone whose hospital is considering this then early registration of interest for 2015 is recommended.
Learn more

NICE recommends rivaroxaban (Xarelto) to prevent blood clots in people who have had a heart attack in final draft guidance

NICE, 23 January 2015
In final draft guidance published today NICE has confirmed its earlier positive draft decision recommending rivaroxaban (Xarelto, Bayer Healthcare), in combination with clopidogrel and aspirin, or with aspirin alone, as an option.
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AliveCor launches ability to detect a serious heart condition in an ECG on a mobile device

prnewswire.com, 22 January 2015
AliveCor, Inc. announced today it has received CE Mark clearance for its automated analysis process (algorithm) to detect atrial fibrillation (AF), the most common heart rhythm disturbance and a leading cause of stroke. 
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ANNEXA-R: Antidote to novel oral anticoagulant met primary endpoint

healio.com, 17 January 2015
Portola Pharmaceuticals announced topline results of the phase 3 ANNEXA-R study demonstrating that andexanet alfa, an antidote to the anticoagulant effects of Factor Xa inhibitors, met the primary endpoint with high statistical significance.
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Identifying postoperative atrial fibrillation in cardiac surgical patients posthospital discharge, using iPhone ECG: a study protocol

BMJ Open, January 2015
Postoperative atrial fibrillation (AF) occurs in 30–40% of patients after cardiac surgery. Identification of recurrent postoperative AF is required to initiate evidence-based management to reduce the risk of subsequent stroke. However, as AF is often asymptomatic, recurrences may not be detected after discharge.
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1 in 10 patients inappropriately prescribed aspirin to prevent first stroke

medicalnewstoday.com, 14 January 2015
More than 10% of patients in the US receiving low-dose daily aspirin to prevent a first heart attack or stroke are likely to have been prescribed the medication inappropriately.
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AtriCure announces preliminary results for fourth quarter and full year 2014 issues 2015 guidance

businesswire.com, 12 January 2015
AtriCure, Inc., a leading innovator in surgical treatments for atrial fibrillation (“Afib”) and Left Atrial Appendage Management (“LAAM”), today announced preliminary financial results for fourth quarter and full year 2014 and issued 2015 financial guidance.
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Antidote reverses anticoagulation activity of rivaroxaban: ANNEXA-R

medscape.com, 9 January 2015
SAN FRANCISCO, CA — Portola Pharmaceuticals, the makers of an antidote for rivaroxaban (Xarelto, Bayer Pharma/Janssen Pharmaceuticals), a factor Xa inhibitor that is part of the newest generation of oral anticoagulants, announced today that a phase 3 study testing the safety and efficacy of the antidote met its primary end point.
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Syncopal episodes can warn of cardiac conditions

jems.com, 8 January 2015
You’ve been dispatched to care for a person who’s unconscious. As you walk in, you’re directed to a young male lying on a couch.
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New study indicates the likelihood of atrial fibrillation increases with second ablation

hcplive.com, 8 January 2015
Researchers enrolled 95 patients who were about to undergo a second ablation procedure and compared the recorded size of each patient’s left atrium before the first ablation with its size before the second procedure.
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FDA approves edoxaban for use in AF-related stroke prevention
forbes.com, 8 January 2015
Late Thursday the FDA announced that it had approved edoxaban, the new oral anticoagulant manufactured by Daiichi Sankyo.
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Dabigatran carries risk of GI bleeding; risk greater in kidney disease, black patients

medicalresearch.com, 7 January 2015
Medical research: What is the background for this study? What are the main findings?
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Timing of ICD implantation affected adverse events

healio.com, 6 January 2015
Implantable cardioverter defibrillator implantation on a weekday morning was safer than implantation that occurred in the afternoon, evening or on a weekend or holiday.
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CardioFocus partners with Japan lifeline for distribution of the HeartLight Laser Balloon to treat atrial fibrillation

prnewswire.com, 5 January 2015
CardioFocus, Inc., developer of the HeartLight® Endoscopic Ablation System for the treatment of atrial fibrillation (AF), today announced that it has executed an exclusive, multi-year distribution agreement with Japan Lifeline Co., Ltd. 
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Study looks at genetic causes of atrial fibrillation

hcplive.com, 2 January 2015
A new genetic analysis of 239 patients provides the new information about which mutations put people at risk of developing atrial fibrillation (AF)
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Digoxin linked to elevated risk for death, hospitalization in patients with AF

healio.com, 29 December 2014
Data from the ATRIA-CVRN study suggest an association between digoxin and increased risk for death and hospitalization in patients with atrial fibrillation.
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ROCKET AF: Oral anticoagulation yielded stroke-protective benefit in AF, valvular disease

healio.com, 26 December 2014
Oral anticoagulation reduced the risk for stroke in patients with atrial fibrillation, even if they had significant valvular disease, according to new data from the ROCKET AF trial.
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New European atlas on the prevention of AF-related stroke launched

arwatch.co.uk, 19 December 2014
The burden of atrial fibrillation (AF)-related stroke prevention in different countries across Europe is shown by a comprehensive new report – ‘The Route Map for Change and European Atlas on the Prevention of AF-related Stroke’ – released recently the Arrhythmia Alliance.
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Lower stroke risk with paroxysmal AF?

medscape.com, 15 December 2014
More evidence suggesting that intermittent atrial fibrillation (AF) may be associated with a lower risk for stroke compared with permanent AF has come from a new systematic review of the literature.
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Working Life: Dr Dermot McCaffrey, consultant cardiologist, Beacon Hospital

irishexaminer.com, 13 December 2014
A day in the life of Dr Dermot McCaffrey.
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Why the sudden onset bruising in a previously stable warfarin patient?

medscape.com, 12 December 2014
A 72-year-old man is your last patient of the day. He is visiting his daughter, a patient of yours, who asks you to see him.
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Atrial fibrillation specific follow-up plan improves post-discharge survivability

hcplive.com, 12 December 2014
Research shows that a follow-up strategy designed specifically for patients who visit the hospital with atrial fibrillation (AF) reduces future admissions and patient deaths more than a general follow-up plan.
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Newer ICD leads associated with low rates of mechanical failure

healio.com, 12 December 2014
Optim-insulated implantable cardioverter defibrillator leads had low rates of all-cause mechanical failure and no observed externalized conductors in a registry study.
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How useful is the RED-AF tool for improving outcomes in patients with atrial fibrillation?

hcplive.com, 10 December 2014
Researchers from Vanderbilt University have developed a new tool for deciding when hospitals should admit patients with symptomatic atrial fibrillation (AF) and when they should send them home.
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Dual-chamber settings in ICDs reduced risk for inappropriate shock

healio.com, 11 December 2014
Compared with single-chamber settings, dual-chamber settings for implantable cardioverter defibrillators were associated with reduced risk for inappropriate shock without increases in morbidity and mortality, according to the results of the OPTION study.
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Biotronik completes full-body ProMRI pacemaker trial

zenopa.com, 11 December 2014
Biotronik has announced the completion of the latest phase of its new ProMRI study, which assesses cardiovascular medical technology equipped with its ProMRI technology.
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Reducing the risk of sudden cardiac arrest during sports

news-medical.net, 11 December 2014
Time and again, the topic of sudden cardiac death grabs the public's attention when football stars or other top athletes collapse from cardiac arrest in front of the live cameras.
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Risk of mortality and cardiovascular outcomes among patients newly diagnosed with atrial fibrillation

BJCardio.co.uk, December 2014
This study aimed to assess mortality and cardiovascular (CV) outcomes of patients with newly diagnosed atrial fibrillation (AF) managed in the UK primary care setting.
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Real-world use affirms NOAC safety profile

medpagetoday.com, 9 December 2014
The bleeding risk profile seen with dabigatran (Pradaxa) and rivaroxaban (Xarelto) in trials of prevention in atrial fibrillation was affirmed in real-world practice.
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BIOTRONIK Announces Conclusion of Full-Body ProMRI Pacemaker Study

businesswire.com, 9 December 2014
BIOTRONIK, a leading manufacturer of cardiovascular medical technology, announced today that Phase B of its ProMRI® study has completed patient enrollment and concluded all planned scans. This phase of the study is investigating the safety of Entovis pacemakers in patients who undergo full-body magnetic resonance imaging (MRI) scans, including cardiac and thoracic spinal scans.
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Study examines patients’ perspectives on deactivation of implantable defibrillators in end-of-life scenarios

dicardiology.com, 5 November 2014
Most patients with implantable cardioverter defibrillators (ICDs) haven’t thought about device deactivation if they were to develop a serious illness from which they were not expected to recover. But given changes in healthcare, there may be a new reason to do so.
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Survey: Doctors believe patients with AF underestimate stroke risk, impact

healio.com, 5 December 2014
Many physicians said they believe that patients with atrial fibrillation underestimate the effect of atrial fibrillation-related stroke on their daily lives and underestimate their risk for ischemic stroke, according to the results of a new survey.
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Unlocking the potential of NOACs

BJCardio.co.uk, December 2014
When the NOACs (novel oral anticoagulants) were introduced over three years ago, they promised to revitalise the management of conditions such as atrial fibrillation (AF), venous thromboembolism (VTE) and thromboprophylaxis after major joint replacement surgery.
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Stroke prevention project in Bradford highlighted in European report

telegraphandargus.co.uk, 4 December 2014
A HIGH-PROFILE European report is highlighting a project being pioneered in Bradford to help prevent strokes in people with a common heart rhythm disorder.
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iRhythm Technologies Receives CE Mark for ZIO® Service, Enters First International Market with CardioLogic Ltd Partnership in United Kingdom

prnewswire.com, 3 December 2014
iRhythm Technologies, Inc., a leading digital health care solutions company focusing on the advancement of cardiac care, today announced that it has secured a CE mark (Conformite Europeenne) for the ZIO Service, enabling the company to market its long-term continuous heart monitoring solution in Europe.
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Epinephrine hurts cardia carrest survival?

medpagetoday.com, 2 December 2014
Epinephrine (adrenaline) given before hospital arrival for cardiac arrest was associated with poorer chances of survival without substantial mental disabili