News & Medical Papers
For current guidelines and updates from within the arrhythmia healthcare community please visit Arrhythmia Watch.
CHMP grants positive opinion for idarucizumab, the specific reversal agent for dabigatran etexilate (Pradaxa®)
Boehringer Ingelheim, 28 September 2015Today, the Committee for Medicinal Products for Human use (CHMP) of the European Medicines Agency (EMA) has issued a positive opinion recommending European approval of idarucizumab (to be marketed as Praxbind®).
European Medicines Agency recommends dabigatran antidote after accelerated assessment
Cardiac Rhythm News, 25 September 2015The European Medicines Agency (EMA) has recommended granting a marketing authorisation, following accelerated assessment, for idarucizumab (Praxbind, Boehringer Ingelheim) as a specific antidote to dabigatran etexilate (Pradaxa, Boehringer Ingelheim) when rapid reversal of its effect is required. Idarucizumab is to be used when a patient taking dabigatran needs to undergo an emergency surgery or when life-threatening or uncontrolled bleeding occurs.
NICE approves new oral anti-coagulant for atrial fibrillation
Nursing Times, 24 September 2015The drug edoxaban has been given the official seal of approval for NHS use in preventing stroke and blood clots in patients with a common heart disorder.
The Beauty of Subcutaneous ICDs Is Not Merely Skin Deep
Cardiovascular Business, 23 September 2015Three decades and 1 million-plus implantations after its introduction, the transvenous implantable cardioverter-defibrillator (T-ICD) is facing stiff competition from a smaller, thinner, more versatile and longer lasting addition to the family tree of implantable devices that shock the heart to prevent sudden cardiac death.
Cohorts, Meta-Analysis: No Link Between Coffee and Increased Risk for Atrial Fibrillation
Medspace, 23 September 2015More research is weighing in with a resounding "no" on whether downing coffee may be detrimental to cardiovascular health in otherwise-healthy adults.
Matters of the heartbeat: Electric irregularity a danger for many
tdtnews, 23 September 2015Dr. Javier E. Banchs, cardiologist Baylor Scott & White — Central Division, director of electrophysiology and pacing, spoke about the medical problem at the Belton Senior Expo on Tuesday.
SJM™ Quadra CRT System
St. Jude Medical, 22 September 2015
The SJM™ Quadra family of devices, with the Quartet™ LV lead, set the standard for quadripolar technology. With 10+ years of design experience, 100+ publications and 100,000+ implants, the SJM Quadra CRT system is pioneering outcomes with proven performance and unmatched data.
The SJM Quadra CRT system is part of the comprehensive heart failure portfolio from St. Jude Medical.
Battery depletion in CRT Defibrillators by vendor
Boston Scientific, 22 September 2015Dr. Ernest Lau's recent independent study showed a clinically meaningful difference in CRT-D longevity by manufacturer at six years.*
Recent ESC Guidelines to Identify Hypertrophic Cardiomyopathy Patients at High Risk for Sudden Death Are Unreliable
Alpha Galileo, 21 September 2015Hypertrophic cardiomyopathy (HCM), a genetic form of heart disease with thick heart walls, is the most common cause of sudden death in patients under 50. While only a minority of patients with HCM are at risk, the implantable cardioverter-defibrillator (ICD) can effectively prevent sudden death in those patients.
FIRST LOOK: Huntsville Hospital expands electrophysiology services
Tech Alabama, 18 September 2015Huntsville Hospital is giving Tech Alabama a first look at its newest electrophysiology lab.
Laguna Pharmaceuticals initiates phase 3 study of vanoxerine in atrial fibrillation and atrial flutter -
Cardiac Rhythm News, 17 September 2015The study, known as RESTORE SR, will enrol 600 patients at trial sites in the USA and other countries and will evaluate vanoxerine at a 400mg dose. In the phase 2b COR-ART study, this dose was effective in restoring sinus rhythm in greater than 80% of patients, a level approaching that of the leading intervention—delivery of electrical shock to the heart with direct current cardioversion.
Catheter Ablation Superior to Drug Therapy for Atrial Fibrillation
HospiMedica, 17 September 2015A new study concludes that first-line treatment with radiofrequency ablation (RFA) is superior to antiarrhythmic drug therapy (AAD) for reducing atrial fibrillation (AF).
Medtronic Wins FDA Clearance For First MRI-Safe ICD
Med Device Online, 16 September 2015Medtronic announced that it has gained U.S. Food and Drug Administration (FDA) approval for the first-ever implantable cardioverter defibrillator (ICD) device that can be safely used by patients undergoing full-body magnetic resonance imaging (MRI) scans.
Health Report: Alternatives to drugs offer new ways to treat Atrial Fibrillation
KUSI News, 16 September 2015According to the National Institute of Health, most adults have an average heart rate of 60 to 100 beats per minute. Most of the time, you don’t think about how fast your heart is beating unless you’re exercising, feeling stressed -- or have cardiac arrhythmia.
Area doctors keep an eye on the heart's electrical system
Portland Tribune, 15 September 2015Electrophysiology is one of the fasted growing fields in cardiac care, and at Northwest Regional Heart and Vascular (Adventist Medical Center in Portland), Dr. Fawaz Alhumaid and colleagues are hard at work analyzing the heart’s rhythm and electrical conduction system.
CardioFocus' HeartLight PMA for the treatment of atrial fibrillation filed and accepted for review by the FDA
Cardiac Rhythm News, 15 September 2015CardioFocus’ Premarket Approval (PMA) application for its HeartLight device has been filed and accepted for review by the US Food and Drug Administration (FDA). The accepted PMA application includes safety and effectiveness data from the company’s multicentre HeartLight pivotal clinical trial, a randomised, controlled study in which a total of 353 patients were treated at 19 leading arrhythmia centres across the USA.
LEADLESS II shows positive safety and efficacy outcomes with Nanostim
Cardiac Rhythm News, 15 September 2015Primary results from the LEADLESS II study have shown positive efficacy and safety outcomes with the Nanostim leadless pacemaker (St Jude Medical) for patients who require a single-chamber ventricular pacemaker.
An aspirin a day DOES help prevent heart attack, stroke and colon cancer - but it's most effective if you're in your 50s
Daily Mail, 14 September 2015A daily low dose of aspirin should be given to people in their 50s to prevent a heart attack or stroke, new guidelines recommend.
3D imaging of kids' hearts
News4Jax, 14 September 2015More than 4 million Americans are living with heart arrythmias meaning they have hearts that don't always beat in a steady rhythm.
Apixaban Cost-Effective in Afib Patients With Low Stroke Risk
Medpage Today, 14 September 2015Treatment with apixaban (Eliquis) versus aspirin was associated with fewer strokes but more bleeding episodes in nonvalvular atrial fibrillation patients with a low risk for stroke in the first study to compare the cost-effectiveness of a non-VKA oral anticoagulant (NOAC) with aspirin in this population.
First MRI-conditional implantable cardioverter defibrillator system receives FDA approval
Cardiac Rhythm News, 14 September 2015Medtronic has announced that it has received the first US Food and Drug Administration (FDA) approval for an implantable cardioverter defibrillator (ICD) system for use with magnetic resonance imaging (MRI) scans.
Stroke Rounds: Anticoagulation After Afib Ablation
Medpage Today, 10 September 2015Atrial fibrillation ablation quells symptoms and has other benefits, but is stroke prevention one of them?
Procedure Does Not Reduce Stroke Risk in Patients with Atrial Fibrillation
HCP Live, 9 September 2015Left atrial appendage obliteration reduces stroke risk in patients with nonvalvular atrial fibrillation (AF), but a new study suggests that the procedure does not reduce stroke risk in AF patients after bioprosthetic mitral valve replacement.
Electrical left atrial appendage isolation helps to improve freedom from long-standing persistent AF
Cardiac Rhythm News, 7 September 2015A randomised, multicentre study has found improvement in the long-term freedom from long-standing persistent atrial fibrillation (AF) in patients who underwent an ablation plus empirical electrical left atrial appendage isolation strategy. No major complications were reported.
ESC: Declining Renal Function May Be Bad News in Afib
MedPage Today, 3 September 2015Patients with atrial fibrillation who also had declining renal function based on estimated glomerular filtration rates (eGFR) were significantly more likely to experience cardiovascular events, researchers reported here.
Stroke Rounds: Seizures More Common in Afib
MedPage Today, 3 September 2015New-onset seizures are more common in atrial fibrillation, possibly linked by silent strokes, an observational study suggested.
ESC: Warfarin May Lower Dementia Risk in Afib Patients
MedPage Today, 3 September 2015Patients with incident atrial fibrillation who were treated with warfarin to reduce the risk of strokes may also have had less chance of developing dementia, researchers suggested here.
Clinical trials launching to test iRhythm Zio Patch for atrial fibrillation screening in nearly 3,000 patients
MedPage Today, 3 September 2015Two major studies are set to launch in the United States and Canada evaluating the use of the Zio Patch, a wearable ECG monitor, to screen for silent atrial fibrillation.
ESC recommends subcutaneous defibrillators for management of ventricular arrhythmias and prevention of sudden cardiac death
Cardiac Rhythm News, 2 September 2015
Updated ESC guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death have been announced during the ESC Congress 2015 (29 August–2 September, London, UK).
Ready for Rio, but sports screening still controversial
European Society of Cardiology, 2 September 2015The most common cause is an underlying genetic condition such as hypertrophic cardiomyopathy. However, as was made clear in a Young Investigators Award study on Sunday, many SCDs in sport may be associated with a structurally normal heart at postmortem examination - and are referred to at autopsy as ‘unexplained’.
ESC: Bleeding Risks Low in 'Real World' Rivaroxaban Patients
Medpage Today, 2 September 2015A required post-marketing study indicates that the anticoagulant rivaroxaban (Xarelto) used for stroke prevention in patients with atrial fibrillation may have less bleeding safety issues than were seen in the drug's pivotal trial, researchers suggested here.
Increase in AED number prompts improved survival
European Society of Cardiology, 2 September 2015A Danish study has found that the survival of cardiac arrest patients following bystander CPR increased from below 10% in 2001 to around 55%in 2012.
AF patients treated with rivaroxaban for stroke prevention experience low rates of bleeding and stroke
News Medical, 2 September 2015Atrial fibrillation (AF) patients treated with rivaroxaban for stroke prevention have low rates of bleeding and stroke, reveals real-world data from the XANTUS study presented at ESC Congress today.
New studies identify gene associated with sudden cardiac death
Cardiac Rhythm News, 1 September 2015First-of-its-kind findings from two independent studies have identified a gene associated with sudden cardiac death.
ESC: Non-Major Bleeding Less Frequent With Apixaban
Medpage Today, 1 September 2015Non-major clinically relevant bleeding events occur more frequently with warfarin than with apixaban (Eliquis) in the ARISTOTLE trial, and carry an increased mortality risk to patients being treated with anticoagulants to prevent strokes caused by atrial fibrillation, researchers reported here.
Diploma in Syncope and related disorders
Royal College of Physicians of Ireland, 1 September 2015
After the success of our inaugural Diploma in Syncope and Related Disorder last year, we are happy to host this programme for 2015-2016.
New ESC Guidelines published on the management of ventricular arrhythmias and prevention of sudden cardiac death
European Society of Cardiology, 31 August 2015The new ESC Guidelines for the management of patients with ventricular arrhythmias (VA) and the prevention of sudden cardiac death (SCD), written by 18 Task Force members and supported by 810 references, are very broad and comprehensive. The document had 74 peer reviewers, and it was our privilege to act as review coordinators.
Medtronic says trials find gene linked to sudden cardiac death
Yahoo News, 31 August 2015Two studies have identified a gene associated with potentially fatal abnormal heart rhythms, device maker Medtronic Plc said on Monday.
Study shows AED usage has increased in public locations, but not at homes
News Medical, 31 August 2015Efforts to improve automated external defibrillator (AED) usage increase bystander defibrillation in public places but not at home, reveals a study of more than 25 000 cardiac arrest patients presented at ESC Congress today by Dr Steen Hansen, a PhD student in the Department of Health, Science and Technology at Aalborg University in Denmark. Efforts included increased numbers of AEDs, cardiopulmonary resuscitation (CPR) education and a nationwide AED registry.
Persistent AF improved by isolation of left atrial appendage
European Society of Cardiology, 31 August 2015In patients with long-standing persistent atrial fibrillation additional electrical isolation of the left atrial appendage (LAA) improved freedom from AF without increasing complications, reported the BELIEF study in the Hot Line session yesterday.
Even watching the World Cup has heart risks
European Society of Cardiology, 31 August 2015During the last three FIFA World Cups football fans experienced abrupt increases in heart rate comparable to that achieved during maximal treadmill exercise testing. Such heart rate changes, suggest French investigators, could be sufficient to increase the risk of cardiovascular events in vulnerable spectators.
No effect of ATP on late AF recurrence
European Society of Cardiology, 31 August 2015Although radiofrequency catheter ablation has been developed as a curative therapy for AF, recurrent atrial tachyarrhythmias are estimated to occur in 30-40% of patients with paroxysmal AF, and 50-70% with persistent or long-lasting AF.
DISCOVERY/OREGON SUDS: Polymorphism in the GNAS Gene Predicts Ventricular Tachyarrhythmias and SCD
American College of Cardiology, 31 August 2015A gene associated with sudden cardiac death in the general population has been identified using implantable cardioverter defibrillator (ICD) monitoring, and may predict ventricular tachyarrhythmias and sudden cardiac death, according to results from the DISCOVERY trial and Oregon Sudden Death Study presented Aug. 31 during ESC Congress 2015 in London.
Manage AFib Risk for Better Health
Wayne County Journal Banner, 31 August 2015Approximately 1.5 million American women live with atrial fibrillation, a heart disorder commonly known as “AFib” that can lead to deadly or life-impairing stroke.
ESC guideline adherent antithrombotic management improves outcomes in AF patients
News Medical, 31 August 2015Patients with atrial fibrillation who receive antithrombotic management according to ESC guidelines have better outcomes than those who do not, according to one year follow up results from the ESC's EORP-AF Pilot General Registry presented today at ESC Congress 20151 and published online in Europace.
BELIEF: Isolating Left Atrial Appendage May Halt Persistent AF
Medscape, 31 August 2015In patients with persistent, recurrent atrial fibrillation (AF), performing electrical isolation of the left atrial appendage (LAA) as well standard catheter ablation and pulmonary-vein isolation may increase the chance of success, according to results from the BELIEF trial.
Multiple risk factors cancel impact of atrial fibrillation on ischaemic stroke risk
Health Canal, 31 August 2015The impact of atrial fibrillation on ischaemic stroke risk in elderly patients is eliminated with multiple risk factors, according to an 11 year study in more than 425 000 patients presented at ESC Congress today.
Cold weather linked to increased stroke risk in atrial fibrillation patients
Medical Xpress, 30 August 2015Cold weather is associated with increased risk of ischaemic stroke in patients with atrial fibrillation, according to research presented at ESC Congress today by Dr Tze-Fan Chao, cardiologist at Taipei Veterans General Hospital and the National Yang-Ming University in Taiwan.
Research Explores Impacts of CPR on Patient Outcomes
American College of Cardiology, 30 August 2015New research presented on Aug. 30 during ESC Congress 2015 in London continues to prove that cardiopulmonary resuscitation (CPR) for out-of-hospital cardiac arrest can improve patient outcomes. However, there is still room for bystander education around CPR and use of automated external defibrillators (AEDs).
Wireless pacemaker gets cautious endorsement
CBS News, 30 August 2015A tiny, wireless pacemaker could offer some heart patients a surgery-free alternative to the traditional devices, a new study says. Some doctors, however, say there are lingering safety questions and warned patients not to rush to get the new technology.
LEADLESS II: Safety and Efficacy of a Leadless Pacemaker
American College of Cardiology, 30 August 2015The leadless cardiac pacemaker may be capable of providing effective pacemaker function in a varied group of patients needing long-term pacing therapy, according to results of the LEADLESS II Trial presented Aug. 30 at ESC Congress 2015 in London, and simultaneously published in the New England Journal of Medicine.
ESC: Leadless Pacemaker Results Promising at 6 Months
Med Page Today, 30 August 2015Device effective in 90% of trial patients, but some concern over adverse event rate
ESC recommends DNA analysis in post mortems of young sudden death victims
Eurek Alert, 29 August 2015ESC Guidelines published today recommend DNA analysis as a fundamental component of post mortem assessment in young sudden death victims. Identification of a genetic cause helps to quickly diagnose and protect relatives.
Cell phones, electronic security systems, music players may affect cardiac devices
European Society of Cardiology, 29 August 2015The role of environmental electromagnetic interference on pacemakers, ICDs and CRT devices will be under the environmental spotlight at a Symposium this afternoon when a session jointly organised with the Asian Pacific Society of Cardiology will consider the impact of mobile phones, security devices, portable headphones and other household devices.
BioControl Medical completes enrolment in the INOVATE-HF study of the CardioFit system to treat heart failure
Cardiac Rhythm News, 28 August 2015BioControl Medical has completed enrolment in its INOVATE-HF (Increase of vagal tone in heart failure) clinical trial evaluating the CardioFit system for the treatment of congestive heart failure. INOVATE-HF has enrolled a total of 725 patients at 86 centres in the USA and Europe, making it the largest prospective, randomised device study to evaluate the treatment of heart failure with vagus nerve stimulation.
Postural modification to the standard Valsalva manoeuvre for emergency treatment of supraventricular tachycardias (REVERT): a randomised controlled trial
The Lancet, 27 August 2015
Background The Valsalva manoeuvre is an internationally recommended treatment for supraventricular tachycardia, but cardioversion is rare in practice (5–20%), necessitating the use of other treatments including adenosine, which patients often find unpleasant. We assessed whether a postural modification to the Valsalva manoeuvre could improve its effectiveness.
Bristol-Myers Squibb and Pfizer to Present New Data on Eliquis (apixaban) at the ESC Congress 2015
Business Wire, 26 August 2015
HARMONY: Ranolazine, dronedarone combination benefits patients with paroxysmal AF
Healio Cardiology Today, 26 August 2015
Published data from the HARMONY trial confirm a previous report that moderate-dose ranolazine plus reduced-dose dronedarone was well-tolerated and reduced atrial fibrillation burden, according to a report in Circulation: Arrhythmia & Electrophysiology.
Lay Summary for research publication on emergency treatment for SVT (supraventricular tachycardias)
Revert, 25 August 2015
Taxonomy of the burden of treatment: a multi-country web-based qualitative study of patients with chronic conditionsBMC Medicine, 30 July 2015
Management strategies for patients with chronic conditions are becoming increasingly complex,
which may result in a burden of treatment for patients.
A-Fib Drug Passes New Test
HCP Live, 27 July 2015
A new sub-analysis of data from the trial known as ROCKET-AF shows that rivaroxaban (Xarelto/Janssen) works as well in patients who have both non-valvular atrial fibrillation (AF) and diabetes as in similar AF patients without diabetes.Read more
Accolade Pacing Systems
bostonscientificmail.eu, 12 May 2015
Discover the World’s First 3T MR-Conditional Pacemaker
Cardiac Rhythm News
www.cxvascular.com, 7 May 2015
Follow the link below to view 'Top stories', 'Features' and 'Industry News' from BIBA Medical Ltd
QiC Awards 2015
Quality in Care (QiC) Anticoagulation is an awards programme to recognise, reward and share good practice in anticoagulation management, education and patient care. The QiC Anticoagulation programme is comprised of a recognition event and subsequent dissemination opportunities for finalists to share good practice and demonstrate the benefits and adaptability of their initiatives to a wider healthcare audience. Gaining recognition through QiC Anticoagulation means an initiative has been highlighted by the NHS, patients and industry as improving patient outcomes and standards of care in the treatment and prevention of blood clots.
Practices to provide warfarin clinics under CCG agreement
pulsetoday.co.uk, 9 April 2015
A CCG-GP ‘partnership’ agreement in Barnsley will fund GPs for visiting elderly or housebound patients at home to conduct medicines reviews and discuss end-of-life care, and increase the number of procedures that can be delivered by practices.
Meta-analysis: Oral anticoagulants superior to warfarin, closure device for stroke prevention
healio.com, 7 April 2015
A systematic review and meta-analysis of randomized controlled trials indicated treatment with novel oral anticoagulants was superior to warfarin and a left atrial appendage closure device for the prevention of stroke in patients with nonvalvular atrial fibrillation.
National Audit of Cardiac Ablation 2013-14
The National Cardiac Rhythm Management Ablation Audit is managed by the National Institute for Cardiovascular Outcomes Research (NICOR), which is part of the National Centre for Cardiovascular Prevention and Outcomes, based at University College London. Specialist clinical knowledge and leadership is provided by the British Cardiovascular Society and British Heart Rhythm Society. The strategic direction and development of the audit is determined by the Audit Steering Group. This includes major stakeholders in the audit, including cardiologists, the professional societies, physiologists, commissioners and patient group representatives.Read response from AF Association
ESC webinar on cardiac resynchronisation therapy: what do the ESC guidelines tell us?
ESC Education, April 2015
On 23 April 2015 from 18:00 to 19:00 CET, join Carsten Israel and Haran Burri for a live webinar focusing on the implementation of the latest ESC Guidelines on "Cardiac Pacing and Cardiac resynchronisation Therapy" through relevant clinical cases.
Support call for a National Service Delivery Model for warfarin patients
scottish.parliament.uk, March 2015
Petition to the Scottish Parliament launched to ensure that ensure that all NHS boards have the resources to assess warfarin patients who request (i.e. self-present) for self-testing and/or self-management their condition.
Currently no such model exists for Scotland's 80,000 warfarin patients.
Oral anticoagulants for stroke prevention in atrial fibrillation | Ten points to remember
acc.org, 27 March 2015
The following are 10 points to remember about anticoagulants for stroke prevention in atrial fibrillation (AF).
Home exercise safe, improves CV performance in adults with ICDs
healio.com, 26 March 2015
In a new study, prescribed home exercise was safe and improved CV performance without increasing the occurrence of shocks, hospitalizations or death among adults with an implantable cardioverter defibrillator for primary or secondary prevention.
Diploma in Syncope and Related Disorders at the Royal College of Physicians of Ireland
Syncope Trust And Reflex anoxic Seizures (STARS), January 2015
This course is the initiative of STARS Trustee, Professor Rose Ann Kenny and Dr Conal Cunningham. Already the positive feedback and uptake is more than encouraging. Syncope units must be the way forward for the future and for anyone whose hospital is considering this then early registration of interest for 2015 is recommended.
2013-14 Cardiac Rhythm Management National Report published
ucl.ac.uk, February 2015
The latest annual report, Heart Rhythm Device Implants and Cardiac Ablation, is now available.
ICD therapy effective in patients with Brugada syndrome
healio.com, 25 March 2015
In patients with Brugada syndrome, implantable cardioverter defibrillator was effective and treated potentially lethal arrhythmias in 17% of patients during a 20-year, single-center study.
Amiodarone associated with acute pancreatitis in patients with AF
healio.com, 24 March 2015
Acute pancreatitis could be an adverse effect of amiodarone use in patients with atrial fibrillation, according to results of a nested case-control study.
Boston Scientific Announces First U.S. Commercial Procedures With The WATCHMAN™ Left Atrial Appendage Closure Device
prnewswire.com, 24 March 2015
This week, three patients in the United States received the first implants of the Boston Scientific Corporation (NYSE: BSX) WATCHMAN™ Left Atrial Appendage Closure (LAAC) Device.
Now published: NICE adoption resources to support NICE guidance that aims to enable people on long-term anticoagulation therapy to self-monitor their blood clotting
National Institute for Health and Care Excellence (NICE), March 2015
These adoption resources have been designed for both clinical and non-clinical staff who are planning to adopt the devices recommended in this guidance (NICE diagnostics guidance DG14 on self-monitoring coagulometers, released September 2014).
Major Implications for new AF Guidelines
hcplive.com, 23 March 2015
A new analysis finds that updates to atrial fibrillation (AF) treatment guidelines will encourage American doctors to prescribe oral anticoagulants to almost 1 million more patients.
Ablation bests amiodarone for treating AF in patients with Heart Failure
medscape.com, 20 March 2015
Long-term results from the Ablation vs Amiodarone for Treatment of Atrial Fibrillation in Patients with Congestive Heart Failure and an Implanted ICD/CRT-D (AATAC-AF) suggest that the procedure is significantly superior to the medication in relieving persistent AF.
AF Ablation at Mitral-Valve Surgery Works, but Without Clinical Gains in Randomized Trial
medscape.com, 20 March 2015
SAN DIEGO, CA — A randomized trial of patients with atrial fibrillation undergoing mitral-valve surgery largely confirmed the 1-year safety and efficacy ...
Ted Robbins: 'I’m lucky to be here' says Phoenix Night comic as he thanks medics that saved his life
manchestereveningnews.co.uk, 22 March 2015
After his dramatic opening night collapse during the Phoenix Nights stage show, Ted Robbins talks to Amanda Killelea about his recovery and how grateful he is.
AF ablation with nMARQ system
prurgent.com, 23 March 2015
Arizona Heart Rhythm Center now with Largest US experience using nMARQ™ Multi-electrode Pulmonary Vein Isolation System for treatment of Paroxysmal Atrial Fibrillation.
Women up to three times more likely to die after stroke
independent.ie, 23 March 2015
Women are dying from stroke three times more often than men in some parts of the country.
Video: Real-world versus clinical trial data with NOACs
radcliffecardiology.com, 20 March 2015
Presented by Paulus Kirchhof, Chair in Cardiovascular Medicine Cardiovascular and Respiratory Sciences at University of Birmingham, UK
Weight loss reduces atrial fibrillation
hcplive.com, 19 March 2015
Rajeev Pathank and colleagues at the Centre for Heart Rhythm Disorders at the University of Adelaide, Canberra, Australia studied AF in 355 patients with a body mass index of 27.
Ablation associated with lower long-term risk of stroke compared to cardioversion in patients with AF
hcplive.com, 18 March 2015
An analysis of more than 20,000 records indicates that patients who choose catheter ablation rather than cardioversion for atrial fibrillation (AF) face an elevated stroke risk immediately after the procedure but a lower stroke risk thereafter.
Community Resuscitation Strategy - Northern Ireland
Building on a commitment in the Service Framework for Cardiovascular Health and Wellbeing, and working with a range of departments and agencies, DHSSPS has developed a Community Resuscitation Strategy for Northern Ireland. The aim is to increase survival for those who suffer an out-of-hospital cardiac arrest by having more people in the community trained to perform CPR and to use an automated external defibrillator.
Heart failure patients need more counseling on defibrillators
hcplive.com, 15 March 2015
Heart failure patients have many treatment options, including--for some--getting an implantable defibrillator. But only about 1 in 5 hospitalized heart failure patients who might benefit from an implantable defibrillators gets pre-discharge counseling on that option, a Duke University study found.
Increased bleeding risks in patients sensitive to warfarin: ENGAGE AF-TIMI 48 analysis
medscape.com, 14 March 2015
Boston Scientific Corporation announced that the FDA has approved the Watchman left atrial appendage closure device.
FDA approves left atrial appendage closure device
healio.com, 14 March 2015
Boston Scientific Corporation announced that the FDA has approved the Watchman left atrial appendage closure device.
First in-man study of miniaturised implantable cardiac monitor shows positive results
cxvascular.com, 12 March 2015
First in-man multicentre study of the miniaturised implantable cardiac monitor Reveal Linq (Medtronic) suggests the device is safe and provides adequate sensing capabilities to detect arrhythmias.
Updated US guidelines suggest an increase by 19% in AF patients recommended for oral anticoagulation
cxvascular.com, 5 March 2015
An assessment of the 2014 American Heart Association (AHA), American College of Cardiology (ACC) and Heart Rhythm Society (HRS) guidelines concerning oral anticoagulation in atrial fibrillation indicates that two-thirds of patients who were not previously recommended for oral anticoagulation therapy are now recommended.
'Digitizing' crosstalk among heart cells may help locate epicenters of heart rhythms
medicalxpress.com, 10 March 2015
A team of scientists led by Johns Hopkins cardiologist and biomedical engineer Hiroshi Ashikaga, M.D., Ph.D., has developed a mathematical model to measure and digitally map the beat-sustaining electrical flow between heart cells.
Intracardiac thrombi rates lower with dabigatran, rivaroxaban, compared with phenprocoumon
healio.com, 6 March 2015
The prevalence of intracardiac thrombi was lower in high-risk patients with atrial fibrillation and flutter treated with direct oral anticoagulants compared with phenprocoumon, according to German researchers.
Safer drug combination found for patients with high-risk atrial fibrillation
medicalxpress.com, 6 March 2015
Patients with high-risk atrial fibrillation, or AFib, often require one drug to regulate heart rhythm and a second drug to thin their blood and reduce the risk of stroke.
CPR devices approved for paramedics
medpagetoday.com, 9 March 2015
The FDA approved the ResQCPR System of two devices for use by first responders doing cardiopulmonary resuscitation (CPR) on people in cardiac arrest.
Atrial fibrillation patients on digoxin face increased risk of death
medicalxpress.com, 4 March 2015
Patients taking digoxin to control atrial fibrillation face a 27 percent greater risk of dying than atrial fibrillation patients who are not taking digoxin, according to an analysis of 19 studies involving more than 500,000 patients scheduled for presentation at the American College of Cardiology's 64th Annual Scientific Session in San Diego.
Anemia linked to adverse outcomes in atrial fibrillation
medicalxpress.com, 4 March 2015
For patients with atrial fibrillation receiving anticoagulant treatment, the presence of anemia is associated with increased risk of thromboembolic events, bleeding complications, and mortality, according to research published online Feb. 13 in the Journal of Thrombosis and Haemostasis.
Case Challenge: A Sudden Increase in INR
medscape.com, 4 March 2015
A 76-year-old man is admitted with increasing shortness of breath. He has a long history of chronic obstructive pulmonary disease (COPD) and has had a recent productive cough. He is admitted to the hospital and treated with amoxicillin, prednisone, codeine, and albuterol.
ECGs for the faint hearted - interpreting ECGs
bjcardio.co.uk, March 2015
In this regular series ‘ECGs for the fainthearted’ Dr Heather Wetherell will be interpreting ECGs in a non-threatening and simple way. In this issue, we apply the knowledge gained so far to a situation that may be encountered in general practice.
Manufacturer of dabigatran files for reversal agent in Europe
pmlive.com, 4 March 2015
Boehringer Ingelheim has surpassed its rivals in the novel oral anticoagulant (NOAC) category by filing a reversal agent for its Pradaxa drug in Europe.
Portola announces full results from positive phase 3 ANNEXA(TM)-R study demonstrating that andexanet alfa rapidly and significantly reversed anticoagulant effect of factor Xa Inhibitor XARELTO
GlobeNewswire.com, 2 March 2015
Portola Pharmaceuticals (Nasdaq:PTLA) today announced full results from the first part of the Phase 3 ANNEXA™-R (Andexanet Alfa a Novel Antidote to the Anticoagulant Effects of fXa Inhibitors – Rivaroxaban) study, which is evaluating the safety and efficacy of andexanet alfa with the Factor Xa inhibitor XARELTO® (rivaroxaban) in healthy volunteers.
Many with AF qualify for oral anticoagulation therapy under new guidelines
healio.com, 2 March 2015
Most patients with atrial fibrillation not recommended for oral anticoagulation under previous guidelines are now eligible for therapy based on the newest guidelines, according to a report published in JAMA Internal Medicine.
Boehringer Ingelheim files BLA for antidote to dabigatran
healio.com, 2 March 2015
Boehringer Ingelheim announced that it has submitted a biologics license application to the FDA requesting an accelerated approval pathway for idarucizumab, an antidote to dabigatran.
Subcutaneous-ICD patients may be able to undergo MRI scans at 1.5T safely
cxvascular.com, 26 February 2015
Subcutaneous implantable cardioverter-defibrillator patients may be safe to be exposed to magnetic resonance imaging (MRI) procedures at 1.5T with a pre-specified scanning and monitoring protocol.
New guidance on managing anticoagulant-associated ICH
medscape.com, 27 February 2015
In the acute phase of oral anticoagulation-associated intracerebral hemorrhage (OAC-ICH), two factors can protect against hematoma enlargement: getting the international normalized ratio (INR) below 1.3 and getting the systolic blood pressure (BP) below 160 mm Hg within 4 hours, a new study shows.
FDA grants orphan drug status to Factor Xa inhibitor antidote
healio.com, 26 February 2015
The FDA has granted orphan drug designation to andexanet alfa for the treatment of patients with serious, uncontrolled bleeding events or who require emergency surgery, according to a press release from the drug’s manufacturer.
Non-medical ILR implants cost-saving
arwatch.co.uk, 25 February 2015
A service has been developed which can safely insert implantable loop recorders (ILRs) in a non-medical, non-catheter laboratory (cath lab) environment, according to a study published recently in the British Journal of Cardiology.