September 2006 - Issue E047

Welcome to the September edition of NICE's monthly E-newsletter.

 
   

New NICE guidelines to improve care for patients with anaemia linked to chronic kidney disease more>>

 
 
 

A round-up of clinical guidance documents that NICE has issued and consulted on during September more>>

 
  Public health evidence documents that NICE has issued during September more>>  
 
  An update on new support for implementation more>>  
 
 

New NICE guidance to improve care for early breast cancer more>>

NICE recommends rituximab for the first line treatment of follicular lymphoma more>>

NICE welcomes bigger role in topic selection process more>>

NICE welcomes new initiative to help NHS reduce spending on treatments that do not improve patient care more>>

NICE welcomes referral of new work programme topics more>>

 
 
  Upcoming events more>>  
 
  Guidance and consultation papers expected to be issued next month more>>  
 
  NICE is the independent organisation responsible for providing national guidance on the promotion of good health and the prevention and treatment of ill health. more>>  
     
 

About the E-Newsletter

The E-newsletter is intended to give everyone working in clinical and public health a regular update on the work of NICE. This includes those working in the NHS, local government, and the voluntary sector covering healthcare professionals, patients, the general public and other stakeholders. Each month it will include a round-up of guidance, consultation papers and public health evidence that has been published, together with information about forthcoming events and a list of guidance the Institute expects to launch next month. The E-newsletter is emailed on the fourth Wednesday of each month to users who have subscribed free of charge on the NICE website and is also available directly on the website.

NICE would welcome your views and comments on the E-newsletter and its content. If you would like to share your thoughts, contact us:

Telephone: 020 7067 5800
Fax: 020 7067 5801
E-mail: nice@nice.org.uk
Letter: NICE, MidCity Place, 71 High Holborn, London, WC1V 6NA

General queries to NICE should be directed to nice@nice.org.uk

 
 
 

New NICE guidelines to improve care for patients with anaemia linked to chronic kidney disease

The National Institute for Health and Clinical Excellence (NICE) and the National Collaborating Centre for Chronic Conditions have today (27 September) published a clinical guideline to improve treatment and care for people with anaemia associated with chronic kidney disease.

The new guideline advises on the detection and diagnosis of anaemia in people with chronic kidney disease, effective treatments, when treatment for anaemia should start, and how clinicians and patients should create a joint treatment plan

A key recommendation is that age alone should not be a determinant for treatment of anaemia of chronic kidney disease. The guideline sets out target haemoglobin (Hb) levels in both adults and children, and levels of Hb at which specified therapies should be given. It also provides detailed advice on initiating, administering and adjusting for erythropoiesis-stimulating agent (ESA) treatment as appropriate.

Professor Peter Littlejohns, Clinical and Public Health Director at NICE and Executive Lead for the guideline, said: “This guideline will help improve the care and treatment of people with anaemia linked to chronic kidney disease. It provides recommendations for supporting patients, by providing information about anaemia of CKD, practical advice on managing their condition and access to a contact who will coordinate their treatment and care. It also gives clear best practice advice to health professionals on the most effective way to provide care, and our implementation advice will support that delivery.”

More information is available on the NICE website.

 

 

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A round-up of clinical guidance documents that NICE has issued and consulted on during September

NICE issued the following guidance this month:

Guidelines

Technology appraisals

Interventional procedures

Public health

  • None

The following consultation documents were issued:

Guidelines

Calls for stakeholder registration:

Scope consultations:

Draft consultations:

  • None

 

Technology appraisals

ACD consultations:

FAD consultations:

  • None

Appeals heard:

  • None

Interventional procedures

 NICE consulted on the following procedures (consultation period 29 August to 26 September)

Public health

Calls for stakeholder registration:

Stakeholder meeting:

  • None

Scope consultations:

Final scope:

  • None

Consultation on draft recommendations:

  • None

Consultation on synopsis of evidence:

  • None

 

 
 

 

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Public health evidence documents that NICE has issued during September

No publications have been issued this month.

 

 
 

 

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Glossary of terms:
Technology appraisals are recommendations on the use of new and existing medicines and treatments within the NHS in England and Wales.
Clinical guidelines are recommendations on the appropriate treatment and care of patients with specific diseases and conditions within the NHS in England and Wales.
Appraisal Consultation Documents (ACDs) set out the independent advisory committee's initial recommendations to NICE based on the evidence for specific medicines and treatments. The consultation period usually lasts 4 weeks.
Final Appraisal Documents (FADs) set out the independent advisory committee’s final recommendations to NICE on specific medicines and treatments following consultation and are used as a basis for NICE guidance. A FAD is usually available for consultation for a period of 15 working days.
Appeals process is the final part of the NICE appraisal process to ensure that the final guidance is robust, where organisations representing patients and carers, healthcare professionals and manufacturers can appeal against final advice given by the independent advisory committee on a specific medicine or treatment.
Final scope - The final scope defines what aspects of care are covered by the guideline (and to whom it applies).
Public health intervention guidance makes recommendations on clear types of activity (‘interventions’) provided by local organisations with public health responsibilities.
Public health programme guidance deals with broader activities for the promotion of good health and the prevention of ill health.
Single Technology Appraisal (STA) is the new rapid process for enabling single new drugs, and existing drugs with new indications, and other treatments to be assessed.

 
 

 

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An update on new support for implementation

Welcome to the implementation section, featuring updates on current work, new resources to support implementation and products coming soon. The implementation website section is at: http://www.nice.org.uk/implementation.

Support materials published this month

Clinical guidelines:

Anaemia management in chronic kidney disease

  • Costing tools – report and template
  • Slide set
  • Implementation advice

Single technology appraisals:

Breast cancer (early) - docetaxel

  • Cost template incorporating report
  • Audit criteria

Non-Hodgkin's lymphoma - rituximab

  • Cost template incorporating report
  • Audit criteria

Coming soon

Several electronic costing reports and local cost templates will be published soon to support forthcoming NICE appraisals on permetrexed disodium for mesothelioma and inhaled insulin for type 1 and 2 diabetes and the clinical guideline update for familial breast cancer.

A slide set, implementation advice and costing tools will be published soon to support the forthcoming NICE guideline on urinary incontinence.

NICE have commissioned the BMJ to produce interactive online educational tools to support NICE guidance on smoking cessation interventions, epilepsy, anxiety and depression and tuberculosis.

Implementation Consultants where you are

NICE field-based Implementation Consultants are approaching all NHS organisations via the Chief Executive offices, to provide a personal update and receive feedback.

Commissioning Guides

Web-based good practice commissioning guides will be available from the NICE website this autumn on the following topics:

  • upper gastrointestinal (GI) endoscopy
  • anticoagulation in atrial fibrillation
  • pulmonary rehabilitation for COPD
  • assisted discharge scheme for COPD
  • assessment of the diabetic foot.

They set benchmarks to determine the level of service needed for a particular topic, link to other sources of information and offer advice on a range of issues, including local needs assessment and opportunities for disinvestment.

 

Shared Learning

We are seeking examples of how NICE guidance has been put into practice to add to our new online database which will be available in the autumn. The purpose of this is to share your experiences that might help others. Visit our website for information.

 

 
 

 

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New NICE guidance to improve care for early breast cancer

NICE has today issued guidance to the NHS on the use of docetaxel and paclitaxel for the treatment of early breast cancer following surgery.

NICE has recommended that:

  • Docetaxel, when given concurrently with doxorubicin and cyclophosphamide (the TAC regimen) in accordance with its licensed indication, is recommended as an option for the treatment of women with early node-positive breast cancer following surgery.
  • Paclitaxel, within its licensed indication, is not recommended for the treatment of women with early node-positive breast cancer following surgery.

Andrea Sutcliffe, Deputy Chief Executive at NICE and Executive Lead for this appraisal, said: “ NICE has issued clear advice to the NHS on the use of docetaxel and paclitaxel for early breast cancer following surgery which will give the best care to patients and use NHS resources most effectively. This is the latest guidance to be developed using the new NICE rapid appraisal process, and we hope to continue to assess individual drugs quickly to provide robust guidance to the NHS close to when they are licensed ”

More information is available on the NICE website.

 

NICE recommends rituximab for the first line treatment of follicular lymphoma

NICE has today issued guidance to the NHS in England in Wales recommending rituximab, within its licensed indications, (that is, in combination with cyclophosphamide, vincristine and prednisolone - or CVP) as an option for the treatment of patients with symptomatic stage III and IV follicular lymphoma who have previously been untreated.

Dr Gillian Leng, Implementation Systems Director and Executive Lead for the appraisal, said: “In 2002 NICE issued guidance recommending the use of rituximab as last-line treatment of stage III or IV follicular lymphoma. Today’s guidance extends the use of this drug to cover first-line treatment, improves the options available to people with this form of cancer and sets clear standards for the NHS in England and Wales on how it should be used .”

More information is available on the NICE website.

 

NICE welcomes bigger role in topic selection process

NICE has welcomed the Department of Health announcement that NICE will play a bigger role in the topic selection process. Topics are the specific treatments, drugs or ways of caring for people with specific conditions or diseases, preventing ill health or promoting good health about which NICE will provide guidance for the NHS and the wider public health community.

The Department of Health today confirmed that NICE will be responsible for the administration of the early stages of topic selection, as well as the organisation of seven new independent consideration panels. The panels will recommend to the Department of Health which topics NICE should produce guidance on. Ministers will continue to make the final decision on which topics are referred to NICE for guidance production.

Andrea Sutcliffe, Deputy Chief Executive at NICE, said: “We welcome these changes to the topic selection process - NICE’s increased role should help the process operate more efficiently, allowing us to start working on topics suggested more quickly, and so produce guidance on selected topics earlier.

“As well as administering the early part of the selection process, we’re also responsible for setting up a range of independent topic selection consideration panels. We are keen to encourage people to contribute to the guidance production process by continuing to suggest topics.”

More information is available on the NICE website.

 

NICE welcomes new initiative to help NHS reduce spending on treatments that do not improve patient care

NICE welcomed the announcement by Health Minister Andy Burnham asking NICE to launch a new programme of work to help the NHS identify interventions that are not effective.

NICE will develop a new set of products to help the NHS make better use of its resources by reducing spending on ineffective treatments, that is, treatments that do not improve patient care or do not represent good value for money. Moving away from ineffective practice will save money that the NHS can invest in drugs and approaches to care that make a positive difference to patients’ lives.

Commenting on the announcement, NICE Chief Executive Andrew Dillon stated:

“NICE already advises the NHS on when it should invest in new drugs and treatments that work well for patients. It’s common sense for us to also advise the NHS on when it is appropriate to stop using treatments that don’t benefit patients or do not represent good value for money where there are better alternatives available.

I would like to encourage anyone who has suggestions for topics that NICE should consider to let us know.”

More information is available on the NICE website.

 

NICE welcomes referral of new work programme topics

NICE has welcomed the referral of additional topics for its forward work programme. Topics referred by the Secretary of State for Health to NICE include eight further public health topics in line with the Institute’s widened remit to include developing guidance on promoting good health and preventing and treating ill health.

In addition, eleven technology appraisal topics have been referred, and the remits fortwo of the nine clinical guidelines topics referred in November 2005 have been amended.

Commenting on the referrals, Andrew Dillon, NICE Chief Executive said: “We welcome the referral of new topics across our work programmes, including the range of public health topics. We will begin work on all the topics as soon as possible and we will make detailed timetables available on our website shortly.”

A list of the topics referred is available on the NICE website.

 
 

 

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Upcoming events

Date for your diary!
NICE 2006: Tackling health priorities

The 2006 annual NICE conference will take place from 6 to 7 December at the ICC in Birmingham.

‘NICE 2006: Tackling health priorities’ will explore issues raised by the increasing expectations of the public and politicians in the context of finite resources, and the challenges facing decision-makers at all levels of the health and social care sectors in using evidence to inform their decisions and in justifying the choices that they make. The conference programme is now available on the NICE website and information on the registration is on the conference website

Urinary incontinence in women – educational day

The Royal College of Obstetricians and Gynaecologists (RCOG) and the National Collaborating Centre for Women and Children’s Health are holding an educational day to coincide with the forthcoming NICE guideline on urinary incontinence in women. The day is for health professionals and patients groups, and takes place on Friday 27th October

More information is available on the RCOG website or by calling the RCOG Conference Office on 020 7772 6245.

 

Tuberculosis – The Way Forward

This joint one-day conference by the Royal College of Physicians and The British Thoracic Society will discuss recent major changes in the NHS’s approach to controlling TB. The NICE guidelines on tuberculosis, published in March 2006, will be one of the developments discussed. Taking place on Monday 16th October, the conference is for clinical and public health professionals.

More information is available on the RCP website..

 
 

 

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October 2006
Clinical and public health guidance to be issued to the NHS

NICE expects to issue the following guidance:

Clinical guidelines

Technology appraisals

  • None

Interventional procedures

Public health

  • None

 

Public health evidence

NICE expects to publish the following evidence documents:

  • None

 

Clinical guidelines and cancer service guidance in progress

NICE expects to issue draft consultation documents on:

Calls for stakeholder registration:

  • None

Draft consultations:

Scope consultations:

None

 

Technology appraisals in progress

NICE expects to issue consultation documents on:

ACDs to be published:

FADs to be published:

Appeals to be heard:

None

 

Interventional procedures in progress

NICE will consult on the following procedures (consultation period 26 September to 24 October ) :

 

Public Health

NICE expects to issue consultation documents on:

Call for stakeholder registration:

Scope consultations:

Stakeholder meetings:

Final scope :

  • None

Consultation on synopsis of evidence:

  • None

Consultation on draft recommendations :

 

 
 

 

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The National Institute for Health and Clinical Excellence (NICE) is the independent organisation responsible for providing national guidance on the promotion of good health and the prevention and treatment of ill health.

NICE will produce guidance in three areas of health:

  • Public health - guidance on the promotion of good health and the prevention of ill health for those working in the NHS, local authorities and the wider public and voluntary sector.
  • Health technologies - guidance on the use of new and existing medicines, treatments and procedures within the NHS.
  • Clinical practice - guidance on the appropriate treatment and care of people with specific diseases and conditions within the NHS.

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